High performance lubricant that brings more to the tablet. We are the leading manufacturer of Microcrystalline Cellulose coated with - RC 581 Grade in the industry. Co-processed excipients deliver functional synergies to address formulation challenges with simplified, single ingredient solutions. Same quality to grades 102/90M, but very low moisture content (< 1.5 %) for processing water-sensitive actives. Safety Data Sheet (SDS) Viewer. Avicel Microcrystalline cellulose is a type of cellulose, a naturally-occurring, large molecular weight polysaccharide found in woody plants. Molecular weight: Not Applicable 1.5. PDF (4.11 mb) Footer menu 1. <<
Manufacturer: FMC BioPolymer. Cellulose microcrystalline for column chromatography. Kristensen, T. Schfer, P. Kleinebudde, Direct pelletization in a rotary processor controlled by torque measurements. /PRNewswire/ -- ReportsnReports added Global Microcrystalline Cellulose (MCC) Market Growth 2019-2024 to its online research database. More than 65 years later, Avicel continues to command global acceptance, with no signs of its popularity waning. Ac-Di-Sol Croscarmellose Sodium is one of our flagship offerings for pharmaceutical manufacturers. SUBSTANCE IDENTIFICATION 1.1. Apply today! The 'Substance identity' section is calculated from substance identification information from all ECHA databases. Generally, these can be classified into two broad groups: Standard grades, and Co-processed grades. gwf;J(e0o|1p{R~P^);ao!%{0KD7. To overcome the pitfalls of known overlays, we tested suspensions of microcrystalline cellulose Avicel RC/CLtrade mark as overlay media in the plaque and plaque-inhibition assay of influenza viruses. ( Eur., JP Product Specifications: Chemical and Physical: Loss on drying 2.0 - 5.0 %* Bulk density 0.29 - 0.36 g/cc Identification A, B Passes Degree of polymerization NMT 350 units pH 5.5 - 7.0* Conductivity NMT 75 S/cm Ui[(lY[|//o)ZmqbQT-Y.M|se[)m?(WRV.W8J/j}9>X.VNsZNOp'^14nuXM%rea5]@ MKnNe MATERIAL SAFETY DATA SHEET Lattice NT Microcrystalline Cellulose MSDS Ref. Revision No. (&E. They are made up of sulfated and non-sulfated repeating units of galactose and 3,6-anhydrogalactose. q9;v80q>jZ !,K`I[O@U|$+i 8sB|+"B@'2^7[2XKrd#5b Van Veen, G.K. Bolhuis, Y.S. 1.3. Page 1 of 8. There may be more fiber in your food than you realized. %PDF-1.4
: 9 This document has been prepared to meet the requirements of the U.S. OSHA Hazard Communication . Quick Links. 3 0 obj
Alubra is also less susceptible to over-blending contributing to more flexible process conditions and reduced waste due to over blended batch failures. MCC helps in the formation of spheres because of its . %
It can be processed both via wet granulation and direct compression, as well as roller compression and extrusion-spheronisation. This grade of polymer film remains intact at pH< 6, thus protecting the API in gastric environments. CAS #: 9004-34-6 . gac74
[#B6`Wnw7 Microcrystalline cellulose is produced by subjecting to a high shear treatment, at elevated temperature and pressure, a reaction mixture of a cellulose material, an active oxygen compound and water, for a time effective to depolymerize the cellulose material. ?t#_n|z%4n#(!:lMD~{mfvv}Na0vx?? xv}O2' H~KEe9>G/,:9\i endobj
IDENTIFICATION OF THE SUBSTANCE/MIXTURE AND OF THE COMPANY/UNDERTAKING 1.1 Product identifiers Product name : Avicel PH-101 Product Number : 11365 Brand : Fluka CAS-No. Alubra sodium stearyl fumarate from IFF Pharma Solutions is a comparatively hydrophilic lubricant widely used in capsule and tablet formulations. Medium size standard MCC grade, suited for the majority of directly compressible actives. CAS 9004-34-6. In extrusion-spheronisation, it is the excipient of choice. ( PROSOLV SMCC, silicified microcrystalline cellulose, is a unique combination of microcrystalline cellulose (MCC) and colloidal silicon dioxide (CSD).A high functionality and multifunctional excipient, it requires less complex processing, has high inherent functionality, and passes that functionality on to the drug formulation. 4 0 obj
They are white to off-white, free-flowing hydrophilic powders supplied in a variety of viscosity grades corresponding to approximate molecular weight, ranging from 100,000 to 7,000,000 daltons. : 5 This document has been prepared to meet the requirements of the U.S. OSHA Hazard Communication Standard, 29 CFR 1910.1200 and Canadas Workplace Hazardous Materials Information System (WHMIS) requirements. If you have Crohn's disease or a history of bowel obstruction, discuss with a doctor or pharmacist about drug interactions with fiber supplements.. 4 0 obj
}o]X4]. Product Name: Microcrystalline Cellulose E460 1.2. Avicel Microcrystalline cellulose also serves as a moisture adsorbent and as a general-purpose formulation improver. A schematic illustration of the manufacturing process for Avicel Microcrystalline cellulose is shown below. The smallest units, the elementary fibrils (cellulose crystalline strands) are made up of many -(1-4) glucose chains which are bundled to form microfibrils. From anti-reflux to biomedical implants, alginates are uniquely suited for a wide range of applications. SDS - Safety Data Sheet. PDF (28.38 mb) 2022 Corporate Fact Sheet. CAS 9004-34-6, pH 5 - 7.5. Material safety data sheet (MSDS) of the m icrocrystalline cellu lose (MCC) The aqueous solution to barrier membrane coating. Heavy metals, % NMT 0.001 LOT #: Available upon request. It is an excipient approved for use in pharmaceutical products and is also GRAS listed and accepted for use as a food additive in Europe and the United States and is included in the FDA Inactive Ingredients Database (oral: powders, suspensions, syrups, and tablets; topical & vaginal products). 1. LATTICE Microcrystalline Cellulose by Dupont, is an alpha cellulose obtained from naturally ocurring cellulose found in wood pulp, which is an equal structuring polysacharide that is found on fruits and vegetables. EMCOCEL XLM 90. Magazine: Material safety data sheet - FMC Corporation. However, with many different grades (standard and specialty) on offer, how do you select the correct material for your needs? Fmc Corporation: Ultra-fine microcrystalline cellulose compositions and process . Comments: The human studies including the use of radiolabelled microcrystalline cellulose show complete absence of digestion or absorption. >>
Microcrystalline cellulose has excellent compressibility properties and is widely used in solid forms such as tablets that are hard, but can dissolve quickly, and this has increased its demand in . if interested in purchasing or obtaining a sample for assessment, you should contact Dupont themselves directly. P}MFbN#[>r(y TEXTURECEL is highly purified sodium carboxymethyl cellulose (NaCMC) that forms clear solutions in water at all temperatures, has exceptional water binding properties, and is available in a wide range of viscosity grades. MATERIAL SAFETY DATA SHEET Avicel PC 611 Microcrystalline Cellulose Page 1 of 8 MSDS Ref. XiDqLN MD'F2`jI7ZWu,JK%5e9~:R>LAm\WyY0lk=ZNP;pZ23)P0GG~%e[ d8GIXRo&. IFF has decades of experience controlling these naturally derived materials, which means you can count on consistent performance, every time. CAS No. Product and Company Identification . Packaging: 34 x 50 kgs fiber drums. Alginate drug delivery harnesses the unique properties of seaweed for premier performance in multiple pharmaceutical and nutraceutical applications; they impart viscosity in solutions and even form a three-dimensional gel in the presence of calcium ions. Material safety data sheet - FMC Corporation. ETHOCEL premium ethylcellulose resins are water-insoluble polymers. Ac-Di-Sol Croscarmellose Sodium is one of our flagship offerings for pharmaceutical manufacturers. GRINDSTED Xanthan Gum is a naturally fermented product of carbohydrates and is applied in various liquid, semi-solid and solid pharmaceutical dosage forms. Learn about our new global sustainability platform, Learn about FMC's industry leading goal of net-zero emissions by 2035, Learn about FMC's differentiated biologically-based crop solutions. Doses up to 30 g per day appear to be . The table below shows the most common physicochemical parameters of this raw material. Instead, they obtained a stable colloidal suspension. bEI3%UxI"M_1)5b/c;/\~3:?/9S\\9/%I3nn2foO^MgX0n: O MSDS Ref. <>
The product range encompasses methylcellulose and hydroxypropyl methylcellulose (hypromellose) each available in different grades to address a wide range of applications including tablet coatings, granulation, controlled release, drug layering, vegetarian hard-shell capsules and amorphous drug stabilization. Eur., JPE . <>
For this reason, nutritionists regard standard powdered microcrystalline cellulose as having zero energy content. G2W4de=u183KGH{ vQ#4:1\wc To help, weve put together a simple guide for selecting Avicel Microcrystalline cellulose grades, with simple explanations of some of the most common grades, plus recommendations that will serve the majority of buyers. The current product range and recommended usage are summarised below: Microcrystalline Cellulose is currently listed in the United States Pharmacopoeia and National Formulary, the European Pharmacopeia, the Japanese Pharmacopoeia, the British Pharmacopoeia, in addition to the Indian and Chinese Pharmacopeia, to name but a few. pfTr^i5wOg)y .6
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{vd^qHe42)Xz[T|[6:q/ i0lGX*}L[7;SGS "lj@::4G[IN{ Foam Booster/Stabilizer; Rheology Modifier; Stabilizer-Emulsion; Suspending Agent . JRS Pharma: PROSOLV SMCC 90 LM: Microcrystalline Cellulose, Colloidal Silicon . Htn@sHaYoEJ*H[G&o)o9;0s N'3[*%M]vAu#9Tqpg9D& : 160182. Performing this action will revert the following features to their default settings: Hooray! The process is relatively basic; and starts with treating cellulose, obtained as a high-grade pulp obtained from fibrous plant material, with mineral acids, followed by purification and spray-drying. SUBSTANCE IDENTIFICATION 1.1. (Microcrystalline Cellulose Market Pr. \C[i+rY2$V,,WT#_)3K?=/fW%[,lE"V?C
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Comprecel MCC (Microcrystalline Cellulose) is a pharmaceutical excipient derived from nature's most abundant and renewable raw material-wood pulp. Microcrystalline Cellulose; Cellulose; Functions. The United States Food and Drug Administration considers microcrystalline cellulose a safe material for all animal species. Avicel co-processed grades are co-spray dried blends of Avicel microcrystalline cellulose with synergistic pharmaceutical excipients to yield functional benefits beyond simple physical blends. They are high molecular weight, highly sulfated, linear molecules with a galactose backbone. The range of products includes three basic types of carrageenan kappa, iota and lambda from various species of red seaweed. q86@on$^X_HuH;3` Material Safety Data Sheet TALSTAR S INSECTICIDE Version 1 Page 1 / 8 SDS # : 6320-A This MSDS has been prepared to meet U.S. OSHA Hazard Communication Standard 29 CFR 1910.1200 and Canada's Workplace Hazardous Materials Information System (WHMIS) requirements. Microcrystalline cellulose (MCC) is one of the most important tableting excipients thanks to its outstanding dry binding properties, enabling the manufacture of tablets by direct compression (DC). JRS Pharma: PROSOLV SMCC 90: Microcrystalline Cellulose, Colloidal Silicon Dioxide: 125: 0.25 - 0.37: Formulas in which a balance of flow and compaction is required. Manufactured by: China . 1.5% w/w), especially designed for formulating active pharmaceutical ingredients (APIs) with a high sensitivity for moisture. AVICEL RC 581. We respect your privacy FMC Privacy Policy. endobj
0.25 - 0.37. stream
When selected in wet granulation, the optimum level of use is between 5 and 20%, although higher levels have been successfully used. Hi, let us know if you have any questions as you visit our website. YUMPU automatically turns print PDFs into web optimized ePapers that Google loves. cas:9004-36-8 msds CELLULOSE ACETATE BUTYRATE. 5 0 obj
Cellulose microcrystalline Revision Date 25-Dec-2021 SARA 313 Not applicable SARA 311/312 Hazard CategoriesSee section 2 for more information CWA (Clean Water Act) Not applicable Clean Air Act Not applicable OSHA - Occupational Safety and Health Administration Not applicable CERCLA Not applicable California Proposition 65 This product contains the following Proposition 65 chemicals. GENERIC EU MSDS - NO COUNTRY SPECIFIC DATA - NO OEL DATA 1. : 51395-75-6 Date Approved: 01/31/2008 Revision No. pb7c8BHqCRX_eL +90w~ gk[YBkf9eDNJdNn q^16mi=4Sr0~{lZ>yvMqS'e,MqB?;Oy9s'$8asJgEh0SS>|J58ub^q
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U%l3K?WW$iJ:tSS8M /&N2R3d2Nl2u]qg*WVkq2lhJZIiE++nKfq)sO~z(d| 7u4w!o}::#l}tEw'M}BEntaugq**t|KZUTe-1J+|. The application areas for Avicel Microcrystalline cellulose are immense and encompass many industrial sectors such as food, pharmaceuticals, and cosmetics. Avicel Microcrystalline cellulose was discovered in 1955 by a team at FMC Corporation, led by the legendary Canadian-born chemist, Orlando Aloysius Battista, which he initially named mechanically disintegrated D.P cellulose. Production of Pharmaceutical Grade Microcrystalline Cellulose. In roller compaction, Avicel Microcrystalline cellulose improves compaction during the ribbon phase, enabling a trouble-free process while also preserving the plasticity of the compacts. AFFINISOL HPMC has been specifically designed for generating solid dispersions via spray-drying (SDD) or hot melt extrusion (HME) in the pharmaceutical industry. A family of polysaccharide products that allow distinctive drug delivery solutions. : CL-611NF Date Approved: 01/13/2010. Delivering efficient and robust formulations. . 0.25 - 0.37. Avicel PC 611 (FMC Biopolymer) Supplied by. J]3yzZ2Z$mZ7o%-Xyq'()V9KX0gk~AA
Cu:3(]N"AQdUt~h|P MSDS Ref. Learn about FMC's differentiated biologically-based crop solutions. : 160182 Date Approved: 05/25/2010 Revision No. It is . Microcrystalline cellulose is an exceptional material and one of the most widely used excipients in the pharmaceutical field. Avicel Microcrystalline cellulose occurs as a white, odourless, tasteless, fibrous powder composed of porous particles. : 5. Similarly, the European Food Safety Agency has also evaluated Microcrystalline cellulose and established that it is not absorbed systemically and excreted unchanged. }[eD-1-8$#Yi^$o8Nc6vwfw;wBT~[Rgi1?%T*/J:/'+Gf'Ae*j@{Rh+2oN|Sbtt;z#v8})F#z=:*]q+U>+ .e
^Q-{@ RPC t/(If>8P&%wNPMJw,VI2aUqRqe3bC,a;C&4RQSf*(=I$r{'%jmk1LUZV(*is6r&wQPAAoID4p?,"lp:wE+)v(_w
'yelVnMh=gIYjK:9v{$G;b8=lGG1_,h^0F2`a~Kusz1p#NS*qt6,F:7+Rma-4u} DINFzJ"Mlctg*~HEge The table below lists the typical nutritional information of microcrystalline cellulose: Quantitative nutritional analysis of Avicel Microcrystalline cellulose (in 100g)1. This paper is based on a study of the interactions that take place during the process of hydrogel formation, break down, and recovery. >z+{!A6wy @nLK3R#hRn sba3;b61V:#Z3X,*?RC!wPmqd7WkA'aZMt6PFV3SEvlY'=p.mn[I{puc\6'ZIyI%rD'zA!"t3I2F ^R;LK,?:&THv*y^K> o0Af?J9J-{s2&cCn)32ADzl%sS5O~J[
It works as a moisture sponge and permits the controlled growth of spheroids. Avicel RC-591 offers ideal thixotropic bahavior for stabilizing suspensions while Avicel CL-611 is a stabilizer for reconstitutable or dry suspension formulations. ( /Group << /S /Transparency /CS /DeviceRGB /I false /K false >>
]c\RbKSTQ C''Q6.6QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ p@" Report Category. Superior Performance: Provides excellent water uptake and rapid swelling . MATERIAL SAFETY DATA SHEET Product Name: MICROCRYSTALLINE CELLULOSE Date/ Revised: 27/November/2012 Page 4 of 4 15. In the late 1960s, Avicel Microcrystalline cellulose was registered in the supplement to the National Formulary as a pharmaceutical excipient. Your file is uploaded and ready to be published. United Nations Sustainable Development Goals, Alginates Protanal, Manucol, Protacid and More, Barrier membrane, Controlled release hydrophilic matrix, Taste masking, Carrageenan Gelcarin, Viscarin and More, Controlled release hydrophilic matrix, Muco-adhesive, Rheology modifier, Rheology modifier/stabilizer, Thin films, Rheology modifier, Rheology modifier/stabilizer, Binder, Controlled release hydrophilic matrix, Rheology modifier, Rheology modifier/stabilizer, Shell - hard capsule, Tablet coatings, Thin films, Topical, Capsules, Other, Solutions, Suspensions, Tablets, Controlled release hydrophilic matrix, Hot melt extrusion, Muco-adhesive, Osmotic pump, Muco-adhesive, Rheology modifier, Rheology modifier/stabilizer, Thin films, Topical. Biologicals by FMC. In summary, Avicel microcrystalline cellulose is virtually inert, its energy content is very low or zero and it is not absorbed. Microcrystalline cellulose is a term for refined wood pulp and is used as a texturizer, an anti-caking agent, a fat substitute, an emulsifier, an extender, and a bulking agent in food production. >>
on Avicel microcrystalline cellulose, the most trusted excipient brand for decades. In Cellulose and Cellulose Derivatives in the Food Industry, T. Wstenberg (Ed. The figure below illustrates the structural organisation of cellulose within plants. A., and Smith, P. A. As some of the data above show, microcrystalline cellulose possesses unique physicochemical properties that set it apart from native cellulose. LATTICE Microcrystalline Cellulose has many important uses within the food, pharma, specialty applications and industrial such as non-stick coatings, insulation of wiring, crop protection and paints,coats and inks. 130. %PDF-1.5
Of all the different brands and grades of MCC, Avicel PH 101 or Emcocel 50 has been the most widely used. Meet our leadership team. Battista, O. FMC BioPolymer 1735 Market Street Philadelphia, PA 19103 (800) 526-3649 . Tel: 1-239-598-5088 sales@espllc.us www.espllc.us. MATERIAL SAFETY DATA SHEET. Unique functionality for a broad range of pharmaceutical applications. Microcrystalline cellulose (Avicel, FMC Corporation) is prepared by acid hydrolysis of cellulose using 2 M hydrochloric acid at 105 C for 15 min. It is made from purified partially depolymerised Alfa cellulose relatively free from both organic and inorganic contaminants. : 9004-34-6 Date Approved: 01/31/2008 . endobj
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It is a white, free-flowing powder. There have always been two different points of view for the liquidity of MCC. stream
Further elaborations can then be performed on the obtained material to produce many other grades of Microcrystalline cellulose. ChemicalBook. Earth Supplied Products LLC. It should be noted that native cellulose itself is completely indigestible, and its hydrolysis during the production of microcrystalline cellulose does not alter its behaviour in the intestine. Test Data Available. Avicel Microcrystalline cellulose is composed of insoluble fibre and does not contribute any other material of nutritional importance. <>
102331. Frijlink, Compaction mechanism and tablet strength of unlubricated and lubricated (silicified) Microcrystalline Cellulose, European journal of Pharmaceutics and Biopharmaceutics, 59 (2005) 133-138. Request media, explore upcoming events and read our latest updates. Buy Chemicals. The polymers added organosolubility further creates advantages for employing HPMC in solvent spray-drying applications. Avicel RC-591 & CL-611 - Description. vdZ@Rgl{eU+7N!3!|hUmW)~}U*7k i@j)q["MEydtP"ftFu]t }JN~A"8lz7#}J.i@
qaj/QU<5OrVMfl{pL? The substance identifiers displayed in the InfoCard are the best available substance name, EC number, CAS number and/or the molecular and structural formulas. <> Microcrystalline cellulose in certain fiber supplements may cause mild side effects ().These may include gas, bloating and increased stool production.. <>/ExtGState<>/Font<>/ProcSet[/PDF/Text/ImageB/ImageC/ImageI] >>/MediaBox[ 0 0 612 792] /Contents 6 0 R/Group<>/Tabs/S>>
The short-term limit for total inhalable dust is 20 mg/m3. cas:9000-11-7 msds Carboxymethyl cellulose. Enter your [postal] code to see information about local products, representatives and retailers, along with special offers in your area. endobj
As one of the most robust and efficient excipients, it tolerates high salt content, high temperature and is stable in a wide pH range. common form is used in vitamin supplements or tablets. 6 0 obj
Pharmacel 112 can be used in a wide range of oral solid dosage (OSD) forms as binder, compressing agent . Aquacoat sustained release coating is a pseudo latex aqueous dispersion of water insoluble polymers used for sustained and enteric coating applications. Avicel Microcrystalline Cellulose: A Guide to Grades and Uses, Working Hours (Mon to Friday): 08:30 - 17:30, legendary Canadian-born chemist, Orlando Aloysius Battista, United States Pharmacopoeia and National Formulary, United States Food and Drug Administration, Quantitative nutritional analysis of Avicel Microcrystalline cellulose (in 100g), https://doi.org/10.1016/0378-5173(95)04231-8, https://doi.org/10.1016/j.ejpb.2004.05.009, https://doi.org/10.1002/9783527682935.ch04, Pharmaceutical Acronyms and Abbreviations, Glossary of Terms Used in the Pharmaceutical Industry, Standard Terms & Conditions Of Sale Of Goods And Services, 4-O-[(1S)-hexopyranosyl]-D-glycero-hexopyranose. Explore our end markets, products, ingredients and essential solutions or get in touch with us about your order. LATTICE Microcrystalline Cellulose by Dupont, is an alpha cellulose obtained from naturally ocurring cellulose found in wood pulp, which is an equal structuring polysacharide that is found on fruits and vegetables. If breathing is difficult or if . Microcrystalline Cellulose / Avicel PH-102. Avicel CL-611 Microcrystalline Cellulose and Sodium Carboxymethylcellulose Page 1 of 9. EMCOCEL 90 M. 130. Since cellulose contains both amorphous and crystalline regions, when the crystalline regions are mechanically and chemically isolated and elaborated, various useful ingredients in the form of cellulose crystals are obtained, one of which is Avicel Microcrystalline cellulose. Avicel PC 611 (FMC Biopolymer) . FMC, JRS and Mingtai were estimated to hold for . /Resources 2 0 R
Combinations of microcrystalline cellulose (MCC) and sodium carboxymethyl cellulose (Na-CMC) are commonly used as stabilising agents and suspending agents in pharmaceutical formulations. X]s
;/4'OslUK:|QY`IL|w @ I!*2T~IN?*}y2*49]yOQ*VG%Gu,;&9zE{q==xvrv}rd(yG*qN6E0K$IBWhe This document has been prepared to meet the requirements of the U.S. OSHA Hazard Communication. The charts below provide guidance on how to select and use standard and co-processed grades of Avicel Microcrystalline cellulose in pharmaceutical products. HMo@9, U Q!R/1*;` zW0}
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3Fz. The cellulose molecule is formed through repeated condensation of cellobiose units. SCMm_>x^O9l (n. Microcrystalline Cellulose (MCC) Manufacturing Industry. The chemical structure of cellulose is shown below: In the biosynthesis of cellulose, two molecules of -D-glucose molecules combine via a condensation reaction (elimination of one molecule of water) to form the so-called cellobiose unit. PRODUCT AND COMPANY IDENTIFICATION PRODUCT NAME: Avicel PC 611 Microcrystalline Cellulose CHEMICAL FAMILY: Carbohydrate, Cellulose Derivative SYNONYMS: Microcrystalline cellulose (INCI name): MCC, cellulose gel; Sodium Carboxymethylcellulose: NaCMC, CMC, SCMC, Carboxymethylcellulose GENERAL USE: Personal Care MANUFACTURER FMC BioPolymer 1735 Market Street Philadelphia, PA 19103 (800) 526-3649 (General Information) msdsinfo@fmc.com (Email - General Information) FMC Europe NV Avenue Mounier 83 1200 Brussels, Belgium 353 21 435 4133 (General Information - Cork, Ireland) 2. GRINDSTED Xanthan Gum readily dissolves in water under ambient conditions without the need of special high-shear equipment. Note that Avicel Microcrystalline cellulose is available in different particle sizes and moisture grades that have different properties and applications. Chemsrc provides Cellulose microcrystalline(CAS#:9004-34-6) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Well-recognized product that can do it all. };khd5x=fr An agricultural sciences company. However, it yields non-digestible fibre. FMC Corporation 2929 Walnut Street Philadelphia, PA 19104 (215) 299-6000 (General Information) . Description: Microcrystalline Cellulose is a term for refined wood pulp manufactured through plant fibre hydrolysis. SDS. To meet their exacting standards, we deliver a wide choice of relevant solutions that are simultaneously replicable, scalable and high performing. In large quantities it provides dietary bulk and may lead to a laxative effect. Pharmacel 112 is a directly compressible microcrystalline cellulose grade with a low moisture content (LOD Max. stream
It is generally regarded as a relatively nontoxic and non-irritant material that is safe for human and animal consumption. Upon ingestion, microcrystalline cellulose is not absorbed into the blood stream and therefore has little toxicological potential. Avicel Microcrystalline cellulose is available in many grades, which differ in particle size, bulk density, and moisture content. Product name: Microcrystalline cellulose; CBnumber: CB4217972; CAS: 9004-34-6; EINECS Number: 232-674-9; Synonyms: MICROCRYSTALLINE CELLULOSE,cellulose; This unique functionality can be used in a diversity of applications such as controlled release dosage forms, enteric coatings, microencapsulation and stabilization in solutions and suspensions.